New research suggests the human papillomavirus vaccine (HPV) can trigger a rare autoimmune brain disorder that causes psychiatric or neurological symptoms following vaccination—and is easily mistaken as psychosis in its early stages.

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A recently published study in Current Medicinal Chemistry identified a possible relationship between anti-N-methyl-d-aspartate (NMDA) receptor encephalitis and HPV vaccination.

Anti-NMDA receptor encephalitis is an acute autoimmune disorder where the body creates antibodies against the N-methyl-D-aspartate receptors in the brain. NMDA is a receptor of the amino acid glutamate. Glutamate is the most abundant excitatory neurotransmitter released by the brain’s nerve cells and plays a crucial role in learning and memory formation.


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